HIGHLIGHTS
SUMMARY
The blood-brain barrier (BBB) limits the delivery of most antitumor drugs and other pharmaceuticals into the brain. The nasal-brain-lymphatic system is discussed as a pathway for brain drug delivery overcoming the BBB. The authors aim to study delivery of the GM1 -liposomes to the mouse brain and fluorescent GBM via the nasal-brain lymphatic system, bypassing the BBB. This series of experi‐ suggest that GBM is characterized by a significant reduction in the transport ments suggest that GBM is characterized by a significant reduction in the transport ofof liposomes in thenasal . . .
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