Intranasal vaccination of hamsters with a newcastle disease virus vector expressing the s1 subunit protects animals against sars-cov-2 disease

HIGHLIGHTS

  • who: Manolo Fernández Díaz from the University of have published the research: Intranasal vaccination of hamsters with a Newcastle disease virus vector expressing the S1 subunit protects animals against SARS-CoV-2 disease, in the Journal: Scientific Reports Scientific Reports
  • what: The authors developed and evaluated three different intranasal vaccine formulations, including an NDV presenting the RBD domain, an NDV presenting the S1 subunit, and a combination of both the RBD domain and S1 subunits.
  • how: Likewise the same result was obtained with the purified recombinant virus (Fig 2B) confirming that . . .

     

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