HIGHLIGHTS
- who: Masashi Ogasawara from the (UNIVERSITY) have published the Article: Intranuclear inclusions in muscle biopsy can differentiate oculopharyngodistal myopathy and oculopharyngeal muscular dystrophy, in the Journal: (JOURNAL)
- how: On immunohistochemistry for anti-PABPN1 in OPMD PABPN1positive aggregates were observed in the myonuclei Data are shown as Mean u00b1 SEM.
SUMMARY
Oculopharyngodistal myopathy (OPDM) is characterized clinically by progressive ptosis, ophthalmoplegia, bulbar muscle involvement, and limb muscle weakness that is predominantly distal and pathologically by the presence of rimmed vacuoles. The authors further counted the number of p62-positive nuclei in the . . .
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