Intratumoral injection and retention hold promise to improve cytokine therapies for cancer

HIGHLIGHTS

  • Who: IL- et al. from the Thomas Jefferson University, United States have published the article: Intratumoral injection and retention hold promise to improve cytokine therapies for cancer, in the Journal: (JOURNAL)

SUMMARY

    In this perspective, the authors advocate for the intratumoral (i.t.) injection of engineered cytokine molecules with optimized tumor retention as a potential solution to overcome the limitations which have thus far hindered the broad adoption of cytokines as safe and effective cancer immuno-therapeutics. As soluble and potent immune activators, cytokines play key roles in orchestrating productive anti-tumor immune_responses . . .

     

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