Intrinsic and extrinsic modulators of the epithelial to mesenchymal transition: driving the fate of tumor microenvironment

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  • who: Salvatore Pucciarelli from the Institute of Physiology Virginia Commonwealth University, United States have published the article: Intrinsic and Extrinsic Modulators of the Epithelial to Mesenchymal Transition: Driving the Fate of Tumor Microenvironment, in the Journal: (JOURNAL) of 14/02/2020
  • what: The current review presents the intrinsic and extrinsic modulators of EMT and their relationship with the TME focusing on the non-cell-derived components such as secreted metabolites extracellular matrix as well as extracellular vesicles. The authors explore how these modulators can be suitable targets for anticancer therapy and personalized medicine. Notch signaling . . .

     

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