Intrinsic folding properties of the hla-b27 heavy chain revealed by single chain trimer versions of peptide-loaded class i major histocompatibility complex molecules

HIGHLIGHTS

• who: Izabela Lenart from the Institut National de la Santu00e9 et de la (INSERM), France Jacobs University Bremen, Germany have published the article: Intrinsic Folding Properties of the HLA-B27 Heavy Chain Revealed by Single Chain Trimer Versions of Peptide-Loaded Class I Major Histocompatibility Complex Molecules, in the Journal: (JOURNAL)

SUMMARY

SCT molecules have been widely used as biological probes for lymphocyte development, activation and to enumerate disease related T_cells. The authors have generated HLA-B27 SCT molecules to address the questions of whether the HLA-B27 HC possesses inherent misfolding properties . . .

 



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