HIGHLIGHTS
- who: Thomas Dittmar from the (UNIVERSITY) have published the paper: Intrinsic signalling factors associated with cancer cell-cell fusion, in the Journal: (JOURNAL)
SUMMARY
The hypothesis that cancer cells can fuse with other cells, such as macrophages, mesenchymal stroma-/stem-like cells (MSC), or further populations, with evolving cancer hybrids of an altered phenotype, was already postulated by the German physician Otto Aichel more than a century ago. Such altered cancer hybrids can exhibit an enhanced metastatic capacity, an increased drug resistance and prospective cancer stem/initiating cells (CS/ ICs) properties as described . . .
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