Intron-derived small rnas for silencing viral rnas in mosquito cells

HIGHLIGHTS

  • who: Priscilla Y. L. Tng and colleagues from the Texas AandM University, College Station, Texas, United States of America, Arbovirus Pathogenesis Group have published the paper: Intron-derived small RNAs for silencing viral RNAs in mosquito cells, in the Journal: (JOURNAL) of February/18,/2022
  • what: The authors report use of a D. melanogaster pre-miRNA-1 stem loop structure within an intron downstream of the constitutively expressed Ae. aegypti polyubiquitin gene (PUb) promoter . The authors provide here a direct comparison between siRNAs that are fully complementary or contain two mismatches against CHIKV reporters, and . . .

     

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