Investigating acoustic startle habituation and prepulse inhibition with silent functional mri and electromyography in young, healthy adults

HIGHLIGHTS

  • What: The whole brain analysis was conducted to explore startle habituation-related activity using cluster-based inference to determine significance (pF the authors and amp;lt; 0.05). The authors aimed to outline the neural correlates of acoustic PPI, of which the previous tactile PPI research in healthy adult populations identified striatal, thalamic, hippocampal, insula, inferior frontal gyrus and supramarginal gyrus/inferior parietal activity on 120 ms SOA PPI condition (Kumari et_al, 2003, 2007). Research is needed to probe low PPI in this instance and would demonstrate the need for a white noise (70 dB) background in . . .

     

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