Investigating mitochondrial fission, fusion, and autophagy in retinal pigment epithelium from donors with age-related macular degeneration

HIGHLIGHTS

  • who: Cody R. Fisher from the DepartmentUniversity of Minneapolis, MN, USA have published the research: Investigating mitochondrial fission, fusion, and autophagy in retinal pigment epithelium from donors with age-related macular degeneration, in the Journal: Scientific Reports Scientific Reports
  • what: As the goal of this treatment was to induce a mitochondrial stress response without cell death, the authors chose a dose of 250 u03bcM C u00ad oCl2. The authors investigated mitochondrial fission, fusion, and mitophagy in human primary RPE cultures to determine if defects in these pathways lead to the accumulation of damaged and dysfunctional . . .

     

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