Investigating the ligand agonism and antagonism at the d2long receptor by dynamic mass redistribution

HIGHLIGHTS

  • who: Lisa Forster from the InstitutUniversity of have published the Article: Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    The expression of the receptor in the CHO-K1 h ­ D2longR cell line was determined by radioligand saturation binding, shown in Supplementary Fig S1 of the Supplementary Information (SI). For the determination of pharmacological parameters under quasi physiological conditions in experiments involving intact cells, an assay temperature of 37 °C should be used. All subsequent experiments were performed at 28 . . .

     

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