Investigating the potential impact of pcsk9-inhibitors on mood disorders using eqtl-based mendelian randomization

HIGHLIGHTS

• who: Alisha Aman and collaborators from the School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom have published the article: Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization, in the Journal: PLOS ONE of December/29,/2022
• what: Although the previous study demonstrated an association between the PCSK9 locus and mood disorder-related traits , here the authors provide evidence that gene-expression modulation of USP24 -and not PCSK9 -is responsible for the causal effects on mood instability, and neuroticism scores.
• how: For positive . . .
  

   

  

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