Investigation of 20s-hydroxyvitamin d3 analogs and their 1α-oh derivatives as potent vitamin d receptor agonists with anti-inflammatory activities

HIGHLIGHTS

  • who: Zongtao Lin from the (UNIVERSITY) have published the Article: Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities, in the Journal: (JOURNAL) of 25/09/2017
  • what: This study shows the potential of the 20S(OH)D3 scaffold for the development of novel anti-inflammatory agents.

SUMMARY

    In this study, side chain modified 20S(OH)D3 analogs (4, 13, 23 and 33) together with their 1α-OH derivatives were synthesized and their metabolism and biological activities tested. 4 . . .

     

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