Investigation of gjb2 and slc26a4 genes related to pendred syndrome genetic deafness patients

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SUMMARY

    Pendred syndrome is a genetic and hereditary disorder 1Department 162 | P a g e that occurs as a result of defects in the function of the SLC26A4 gene. As mentioned, the SLC26A4 gene encodes the pendrin protein. Since potassium, sodium, and chlorine ions are very important for hearing, a defect in the SLC26A4 gene causes disruption in the transmission of sound waves to the brain and reduces the sense of hearing. GJB2 and SLC26A4 genes are common deafness genes and account for 40% of genetic deafness patients. The aim of this study is to . . .

     

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