Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on dna methylation and rna expression in human brain

HIGHLIGHTS

  • who: Ming D. Li from the Tulane University, United States have published the research work: Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain, in the Journal: (JOURNAL)
  • what: For the first time, the authors intended to link SNPs, DNA methylation, mRNA expression, and smoking status together within a single cohort`s study. Analysis, an asymptotic p-value from the Wald statistic was obtained as a measure of association for each variant with any extent of expression or methylation of a given gene.
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