Investigational cyclin-dependent kinase 4/6 inhibitor glr2007 demonstrates activity against isocitrate dehydrogenase wild-type glioblastoma and other solid tumors in mice xenograft models

HIGHLIGHTS

• who: Lei Yin from the Genentech, Inc, United States have published the Article: Investigational cyclin-dependent kinase 4/6 inhibitor GLR2007 demonstrates activity against isocitrate dehydrogenase wild-type glioblastoma and other solid tumors in mice xenograft models, in the Journal: (JOURNAL)
• what: This study demonstrated the activity and efficacy of a novel investigational CDK4/6 inhibitor GLR2007 in preclinical models of solid tumors including GBM, and lung, liver, breast, and colorectal cancers. Although the relative distribution of GLR2007 to the brain is low compared to other tissues, this study shows the potential of administration of . . .
  

   

  

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