HIGHLIGHTS
- who: Xinwen Zhang from the Center of Implant Dentistry, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key have published the research work: Ion Channel Dysfunction in Astrocytes in Neurodegenerative Diseases, in the Journal: (JOURNAL)
- what: More specifically, this study showed that Aβ triggers TRPA1 to induce Ca2+ inward flow in astrocytes, thereby activating nuclear factor (NF)-κB, serine/threonine-protein phosphatase 2B (PP2B), and nuclear factor of activated T-cells (NFAT), which resulted in inflammatory responses. This study showed that AQP4 is not permeable to MPP+. The study also analyzed the specific . . .
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