Ip3r2 levels dictate the apoptotic sensitivity of diffuse large b-cell lymphoma cells to an ip3r-derived peptide targeting the bh4 domain of bcl-2

HIGHLIGHTS

• who: H Akl from the LaboratoryUniversity of, Wako, Japan have published the paper: IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2, in the Journal: (JOURNAL)
• what: The authors focused on BH3-profiled ‘primed to death' DL-BCL cell lines that are dependent on Bcl-2 upregulation . The authors focused on comparing SU-DHL-4 and OCI-LY-1, because these cells are both germinal-center DL-BCL cells and are very similar in cell size .
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