Ipscs derived from infertile men carrying complex genetic abnormalities can generate primordial germ-like cells

HIGHLIGHTS

  • who: Auru00e9lie Mouka from the Facultu00e9 have published the article: iPSCs derived from infertile men carrying complex genetic abnormalities can generate primordial germ-like cells, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    Primed iPSCs from DSD patient (patient 2) were generated from erythroblasts following the protocol previously described for patient 1­ 24. The authors investigated the pluripotency of five patient 2 primed iPSCs clones, by analyzing the expression of the endogenous pluripotency marker genes SOX2, OCT4, NANOG by RT-PCR. Pluripotent stem_cells exist in a naive or primed state, respectively represented by . . .

     

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