Iqgap1 in podosomes/invadosomes is involved in the progression of glioblastoma multiforme depending on the tumor status

HIGHLIGHTS

• who: Deborah Rotoli et al. from the Laboratorio Biologu00eda del Desarrollo, UD Bioquu00edmica y Biologu00eda Molecular and Centro (CIBICAN), Universidad, Via Sergio Pansini, Naples, Italy have published the article: IQGAP1 in Podosomes/Invadosomes Is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status, in the Journal: (JOURNAL)
• what: The authors show evidence of IQGAP1 involvement in GBM onco-biology, including glioma-infiltrating myeloid cells (GIMs), remaining neurons, endothelial vascular cells, and astrocytes.

SUMMARY

IQGAP1 connects elements of the cytoskeleton to cell adhesion and some signaling molecules and thus . . .

 



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