Ire1 inhibitors as a promising therapeutic strategy in blood malignancies

HIGHLIGHTS

  • who: Wojciech Wiese and colleagues from the Department of Clinical Chemistry and Biochemistry, Medical University of Lodz, Lodz, Poland have published the paper: IRE1 Inhibitors as a Promising Therapeutic Strategy in Blood Malignancies, in the Journal: Cancers 2022, 14, 2526. of /2022/
  • what: Blood cancers, which comprise several types of leukemia, lymphomas, and myeloma, can develop from various types of blood cells at any level of their differentiation, and thus, they constitute a highly heterogeneous group of neoplasms.
  • how: The MKC-8866 IRE1u03b1 inhibitor was tested in Philadelphia-positive (Ph+) ALL cells simultaneously . . .

     

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