Irinotecan and its metabolite sn38 inhibits procollagen i production of dermal fibroblasts from systemic sclerosis patients

HIGHLIGHTS

  • who: J. Lapoirie from the CNRS have published the Article: Irinotecan and its metabolite SN38 inhibits procollagen I production of dermal fibroblasts from Systemic Sclerosis patients, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    The level of procollagen I release was presented as fold change compared with the procollagen I release by the same non-treated fibroblasts arbitrary fixed at 100%. | Vol:(1234567890) 11:18011 | None Production of procollagen (%) Production of procollagen (%) Irinotecan ( g/mL) None Irinotecan ( g/mL) significance was evaluated using paired t-test. Incubation with 0.3 µg/mL SN38 . . .

     

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