Iron metabolism and ferroptosis in type 2 diabetes mellitus and complications: mechanisms and therapeutic opportunities

HIGHLIGHTS

  • who: Runyu Miao from the (UNIVERSITY) have published the paper: Iron metabolism and ferroptosis in type 2 diabetes mellitus and complications: mechanisms and therapeutic opportunities, in the Journal: (JOURNAL) of 23/Nov/2022
  • future: Research is required to clarify the relationship between the mitochondrial oxidation capacity of adipocytes and iron regulation.

SUMMARY

    During iron metabolism, less than 10% of the iron demand is met by intestinal absorption, and the remaining iron is exported by ferroportin. Abnormal iron metabolism mainly presents as iron deficiency or overload, which triggers multiple pathological changes such . . .

     

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