Is the stalk of the sars-cov-2 spike_protein druggable?

HIGHLIGHTS

  • who: Ludovico Pipitu00f2 and collaborators from the Centre for Sport, Exercise and Life Sciences, Faculty of Health and Life Sciences, Coventry University, Coventry , FB, UK have published the article: Is the Stalk of the SARS-CoV-2 Spike_Protein Druggable?, in the Journal: Viruses 2022, 14, 2789. of /2022/
  • what: Since this approach has yet to yield suitable small_molecule inhibitors, the authors have investigated the druggability of the conserved region of the flexible stalk region within subunit S2 by combining molecular docking with high-throughput molecular dynamics simulations.
  • future: Future studies could therefore be . . .

     

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