Ishophloroglucin a ameliorates vegf-induced epithelial-mesenchymal transition via vegfr2 pathway inhibition in microgravity-stimulated human retinal pigment epithelial cells

HIGHLIGHTS

  • who: Myeongjoo Son and colleagues from the Inha Research Institute for Aerospace Medicine, Inha University, Incheon, Korea have published the research: Ishophloroglucin A Ameliorates VEGF-Induced Epithelial-Mesenchymal Transition via VEGFR2 Pathway Inhibition in Microgravity-Stimulated Human Retinal Pigment Epithelial Cells, in the Journal: Antioxidants 2022, 11, x FOR PEER REVIEW of 22/Oct/2022
  • what: Actin cytoskeleton regulators were modulated in microgravity-stimulated ARPE19 cells.
  • how: The in silico results showed that IPA had the greatest binding_energy with VEGFR2 among the VEGFRs even benzimidazole urea as a VEGFR2 antagonist .

SUMMARY . . .

 

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