Ism1 suppresses lps-induced acute lung injury and post-injury lung fibrosis in mice

HIGHLIGHTS

  • who: Ngan Nguyen from the Department of Biological Sciences, Faculty of Science, National University have published the paper: ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice, in the Journal: (JOURNAL)
  • what: The authors investigated how ISM1 influences LPS-induced acute pulmonary inflammation using Ism1-/- mice and intranasal instillation of recombinant ISM1 (rISM1). Using a mouse cytokine antibody array and whole lung lysates, the authors show that at 24 h post-LPS challenge, seven cytokines/ chemokines were substantially elevated (u2265 1.5-fold) in Ism1-/- lung compared with those in . . .

     

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