Isolation, bioassay and 3d-qsar analysis of 8-isopentenyl flavonoids from epimedium sagittatum maxim. as pde5a inhibitors

HIGHLIGHTS

• who: Juntao Li from the Institute of Traditional Chinese Medicine, Shanghai University of Traditional Shanghai, People`s Republic of China have published the Article: Isolation, bioassay and 3D-QSAR analysis of 8-isopentenyl flavonoids from Epimedium sagittatum maxim. as PDE5A inhibitors, in the Journal: (JOURNAL)
• what: The authors aimed to initially reveal the PFES efficacy mechanism for treating ED.
• how: The QC results showed that the screening assay was stable reproducible reliable and low cost for PDE5A1 inhibitors screening. The research results showed that icariin inhibited PDE5A1 with u00adIC50 of 8.28 u03bcM . . .
  

   

  

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