Isolation of the so4-4-galnacβ1,4glcnacβ1,2manα-specific receptor from rat liver*

HIGHLIGHTS

• who: Dorothy Fiete from the have to be re-evaluated in light of the current findingsIt is not surprising that it has been difficult to purify the Man-R from liver using affinity chromatography on immobilized ligands containing terminal mannose, procedures that are effective for isolation of the Man-R from lung (24), macrophage lines (26), and placenta (25), in light of the properties of the S GGnM-R. It now seems likely that the S GGnM-R we have isolated from liver accounts for a major fraction of binding and internalization of ligands containing terminal Man . . .
  

   

  

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