Isoprenaline modified the lipidomic profile and reduced β-oxidation in hl-1 cardiomyocytes: in vitro model of takotsubo syndrome

HIGHLIGHTS

  • who: Jan Polak from the Leiden University, Netherlands Shanghai Jiao Tong University, China have published the paper: Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes: In vitro model of takotsubo syndrome, in the Journal: (JOURNAL)
  • what: The authors focused on mitochondrial bioenergetics and metabolism (e_g, the production of ATP from fatty_acid oxidation), changes in the lipidomic profile, and the gene and protein expression of essential_fatty_acid transporters, i.e., differentiation Cluster 36 (CD36), long-chain fatty_acid transport protein (FATP4), and carnitine palmitoyl transferase 1b (CPT1b) during catecholamine exposure. The study demonstrates that . . .

     

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