Isorhapontigenin modulates sox9/tollip expression to attenuate cell apoptosis and oxidative stress in paraquat- induced acute kidney injury

HIGHLIGHTS

  • who: Qiang Zheng and collaborators from the Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China have published the paper: Isorhapontigenin Modulates SOX9/TOLLIP Expression to Attenuate Cell Apoptosis and Oxidative Stress in Paraquat- Induced Acute Kidney Injury, in the Journal: Oxidative Medicine and Cellular Longevity
  • what: This study demonstrated that ISO modulated SOX9/TOLLIP expression to attenuate cell apoptosis and oxidative stress in PQ-AKI suggesting the potential of ISO in treating PQ-poisoned patients. The authors explored the effects of ISO on PQ-AKI, mainly focusing on its antiapoptotic . . .

     

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