Isorhynchophylline ameliorates stress-induced emotional disorder and cognitive impairment with modulation of nmda receptors

HIGHLIGHTS

  • who: Chen Wang from the Chinese Academy of Medical Sciences China Federal University of Pampa, Brazil have published the Article: Isorhynchophylline ameliorates stress-induced emotional disorder and cognitive impairment with modulation of NMDA receptors, in the Journal: (JOURNAL) of 15/Dec/2022
  • what: This study is to investigate whether isorhynchophylline has protective effect against stress-induced emotional disorders and cognitive impairment.
  • how: The results showed that isorhynchophylline improved CUMS-induced weight loss anxiety- and depression-like behaviors and spatial memory impairment. Glutamate and the expression of GluN2B increased in the CUMS mice while . . .

     

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