HIGHLIGHTS
SUMMARY
Most investigations into the role of glutamine have focused on the impact of glutamine metabolism in TILs in_vitro, while largely ignoring the impact of glutamine on tumor cell division and function in the in_vivo tumor microenvironment (TME). The study seeks to combine in_vivo and in_vitro studies implanting [13C] tracer methodology combined with gas and liquid chromatography-based analysis to address these gaps. Most of these studies, however, were conducted in an in_vitro T_cell culture system and lack in_vivo evidence to confirm the physiologic impact of T_cell metabolism on tumor cells in the TME. Unlike . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.