Isotype-specific degradation of rac activated by the cytotoxic necrotizing factor 1*

HIGHLIGHTS

• who: Marius Pop from the (UNIVERSITY) have published the research work: Isotype-specific Degradation of Rac Activated by the Cytotoxic Necrotizing Factor 1*, in the Journal: (JOURNAL) of April/20,/2004
• what: By overexpressing His-tagged activated Rac mutants the authors show that constitutive activation is necessary for degradation of Rac. The authors show that CNF1-induced Rac degradation is even isotype-specific, and the authors identify the amino_acids in Rac which defines this specificity. The authors attempted to characterize the structural and functional requirements for degradation of activated Rac.
• future: Studies are . . .
  

   

  

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