Jak inhibitors disrupt t cell-induced proinflammatory macrophage activation

HIGHLIGHTS

• who: Mukanthu H Nyirenda u200d and colleagues from the School of Infection and Immunity, University of Glasgow and Life Sciences, Glasgow, UK have published the research: JAK inhibitors disrupt T cell-induced proinflammatory macrophage activation, in the Journal: (JOURNAL) of 14/08/2022
• what: The authors investigated the effect of JAK inhibitors on the generation of cytokine-u00adactivated T (Tck) cells and the production of cytokines and chemokines induced by Tck Additional supplemental material is published online only. cell/macrophage+ interactions. The authors show that tofacitinib and ruxolitinib, two structurally unrelated small_molecule inhibitors, inhibit the . . .
  

   

  

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