Jejunum-derived nf-κb reporter organoids as 3d models for the study of tnf-alpha-induced inflammation

HIGHLIGHTS

  • who: Hellen Daghero from the Faculty University have published the article: Jejunum-derived NF-u03baB reporter organoids as 3D models for the study of TNF-alpha-induced inflammation, in the Journal: Scientific Reports Scientific Reports of 23/08/2021
  • what: This study proposes novel NF-u03baB reporter intestinal organoids as a 3D model to study small intestine inflammation in health and disease.
  • future: Implementation of these models in co-culture systems with immune cells and/or microorganisms and the use of gene editing tools to alter specific steps in the NF-u03baB pathway . . .

     

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