Jian-pi-yi-shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of pof

HIGHLIGHTS

  • who: Xiao-Lin Jiang et al. from the Department of Nephrology, The Fourth of Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Shenzhen, China have published the research work: Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF, in the Journal: (JOURNAL)
  • what: The authors isolated mitochondria and showed that CTX damaged mtDNA, disrupted mitochondrial respiratory function, and produced ROS, thereby causing ovarian injury.
  • how: The results showed that JPYS affected the expression of ASK1/JNK pathway-related proteins inhibited ASK1 and JNK phosphorylation . . .

     

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