Jmjc family of histone demethylases form nuclear condensates

HIGHLIGHTS

• who: Marta Vicioso-Mantis and collaborators from the Department of Molecular Genomics, Instituto de Biología Molecular de Barcelona (IBMB) have published the research: JmjC Family of Histone Demethylases Form Nuclear Condensates, in the Journal: (JOURNAL)
• what: The authors show that the JMJC-KDMs contain low-complexity domains and intrinsically disordered regions (IDR) which in some cases reached 70% of the protein. The authors show that they are prone to phase separation and that representative examples from nuclear condensates are important for their functional outcome. The current model proposes that phase-separated condensates regulate gene . . .
  

   

  

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