Joint infection systemic rifampicin shows accretion to locally implanted hydroxyapatite particles in rat abdominal muscle pouch model

HIGHLIGHTS

  • who: Sujeesh Sebastian et al. from the of Clinical Sciences, Orthopaedics, Faculty of Medicine, Lund University, Lund, Sweden have published the research: Joint Infection Systemic rifampicin shows accretion to locally implanted hydroxyapatite pArticles in rat abdominal muscle pouch model, in the Journal: (JOURNAL)
  • what: The aim of this in_vivo study was to test if systemically administered rifampicin could replenish HA-based biomaterials with or without prior antibiotic loading to protect the material from late bacterial repopulation. Since the study showed a significant antibacterial effect of CaS/HA-VAN pellets following RIF biomodulation, clinically the ideal . . .

     

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