Kcc3a, a strong candidate pathway for k loss in alkalemia

HIGHLIGHTS

  • who: KCC and collaborators from the Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, United States, Division of Nephrology have published the Article: KCC3a, a Strong Candidate Pathway for K Loss in Alkalemia, in the Journal: (JOURNAL)
  • what: The authors show abundant expression of KCC3a in intercalated cells type-B or type-nonA/nonB. The authors propose that coupling of pendrin function with KCC3a function results in KHCO3 secretion and that KCC3a might be a key pathway for K+ loss in metabolic alkalosis. The authors provide here the first report of a K . . .

     

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