Kdm2 family members are regulated by hif-1 in hypoxia

HIGHLIGHTS

• who: Michael Batie and colleagues from the Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dow street, Dundee have published the paper: KDM2 Family Members are Regulated by HIF-1 in Hypoxia, in the Journal: (JOURNAL)
• what: The authors show that hypoxia results in increased mRNA levels for human lysine (K)-specific demethylase 2 (KDM2) family members KDM2A and KDM2B and also for Drosophila melanogaster a histone and protein demethylase. The authors demonstrate that in human cells KDM2A regulation by hypoxia and HIF-1 occurs at the level of promoter . . .
  

   

  

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