Keeping relapse in chk: molecular mechanisms of chk1 inhibitor resistance in lymphoma

HIGHLIGHTS

  • who: Commentary and colleagues from the DepartmentYale University have published the research: Keeping RelApse in Chk: molecular mechanisms of Chk1 inhibitor resistance in lymphoma, in the Journal: (JOURNAL) of 23/Nov/2022
  • what: This experiment provides important insight into the mechanisms driving resistance in different genetic backgrounds. This work provides important insight into how Chk1 abundance and activity is regulated to confer resistance to treatment with inhibitors.
  • future: The most up-to-date-version is available at https//doi.org/10.1042/BCJ20220461 New perspectives on relationship between Claspin and cancer initiation and . . .

     

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