HIGHLIGHTS
- who: Omar Prado-Carrillo and collaborators from the Laboratorio de Fármaco-Oncología, Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Posgrado en Ciencias Bioquímicas, Universidad Nacional Autónoma de México (UNAM)Ciudad de Mexico, Mexico have published the article: Ketoconazole Reverses Imatinib Resistance in Human Chronic Myelogenous Leukemia K562 Cells, in the Journal: (JOURNAL)
- what: This study explored apoptosis as a possible mechanism of growth inhibition by the combination treatment. The authors propose that ketoconazole stimulates apoptosis through COX-2 inhibition, in addition to P-gp inhibition . . .
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