Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2d and 3d ovarian and breast cancer in vitro models

HIGHLIGHTS

  • who: Simona Dobiasovu00e1 from the DepartmentUniversity have published the article: Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D ovarian and breast cancer in vitro models, in the Journal: Scientific Reports Scientific Reports of 25/Nov/2021
  • what: In the study , eight ketone-selenoesters and seven cyanoselenoesters were evaluated for their anticancer and MDR modulation potential using 2D and 3D cultures.
  • how: The most significant result was shown by compound K7 for the Adriamycin-resistant cell line (HOC/ADR) . For the detection of P-gp inhibitory potential the . . .

     

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