Kinase signaling initiates coat complex ii (copii) recruitment and export from the mammalian endoplasmic reticulum*

HIGHLIGHTS

  • who: Meir Aridor from the (UNIVERSITY) have published the article: Kinase Signaling Initiates Coat Complex II (COPII) Recruitment and Export from the Mammalian Endoplasmic Reticulum*, in the Journal: (JOURNAL) of July/11,/2000
  • what: The authors show that Sar1 recruitment to ER membranes is sensitive to kinase activation, demonstrating that the first step in COPII vesicle formation, Sar1 activation, is under kinase regulation. The authors propose that the ability of the ER export machinery to integrate with kinase signaling cascades may represent an important first step in the general function of cargo selection by COPII . . .

     

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