Kindlin-2 promotes chondrogenesis and ameliorates il-1beta-induced inflammation in chondrocytes cocultured with bmscs in the direct contact coculture system

HIGHLIGHTS

  • who: Kindlin- and collaborators from the Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China have published the research work: Kindlin-2 Promotes Chondrogenesis and Ameliorates IL-1beta-Induced Inflammation in Chondrocytes Cocultured with BMSCs in the Direct Contact Coculture System, in the Journal: Oxidative Medicine and Cellular Longevity of 11/04/2022
  • what: The authors demonstrated that Kindlin-2 and its activated PI3K/AKT signaling played an essential role in promoting extracellular matrix (ECM) secretion and ameliorating IL-1beta-induced inflammation in chondrocytes cocultured with bone marrow stem cells (BMSCs . . .

     

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