HIGHLIGHTS
- who: Deborah A. Enke from the (UNIVERSITY) have published the research: Kinetic Analysis of the Cyclin-dependent Kinase-activating Kinase (Cak1p) from Budding Yeast*, in the Journal: (JOURNAL) of July/13,/2000
- what: The authors explore the kinetics of CDK phosphorylation by Cak1p, and the authors examine the role of the catalytic step in the reaction mechanism.
- how: For these studies the authors used a human CDK2 substrate rather than the endogenous yeast CDK Cdc28p.
SUMMARY
Cak1p appears to bind ATP differently than do other protein_kinases. Remarkably, Cak1p can . . .
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