Kinetic pathway of pyrophosphorolysis by a retrotransposon reverse transcriptase

HIGHLIGHTS

• who: Retrotransposon Reverse Transcriptase and collaborators from the Rutgers University have published the paper: Kinetic Pathway of Pyrophosphorolysis by a Retrotransposon Reverse Transcriptase, in the Journal: (JOURNAL)
• what: The authors have examined the determinants of pyrophosphorolysis of a retrotransposon reverse_transcriptase.
• how: The results indicated that the rate constant for single nucleotide addition (kpol) was reduced 223 fold for the mutant enzyme relative to WT but that nucleotide binding was unaffected. Since this could give further insights into the functions of the D211 residue the authors carried out a series of experiments to characterize . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.