Kinetics and phospholipid specificity of apolipoprotein n-acyltransferase

HIGHLIGHTS

  • who: Falk Hillmann from the (UNIVERSITY) have published the research work: Kinetics and Phospholipid Specificity of Apolipoprotein N-Acyltransferase, in the Journal: (JOURNAL) of August/12,/2011
  • how: These results showed that purified Lnt is mainly unacylated but in an active conformation such that it can attack the sn-1-acyl chain of a phospholipid and become acylated. To overcome this problem the authors analyzed whether a synthetic diacylated lipopeptide could be used as a substrate to study Lnt activity. Acyl Chain Specificity-In a second approach the authors studied the effect of the acyl . . .

     

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