Kinetics of mrna nuclear export regulate innate immune response gene expression

HIGHLIGHTS

SUMMARY

Considering mRNA, the gene_expression intermediate whose cytoplasmic presence allows for protein synthesis, its cytoplasmic abundance is a function of numerous molecular reactions that are grouped within the broader terms of nuclear mRNA synthesis (transcription initiation, elongation), mRNA processing and export (e_g, capping, splicing, polyadenylation, and transport), and cytoplasmic degradation. Studies of immune_response gene_expression have been insightful as the dynamical nature of immune gene_expression reveals the underlying kinetics of the regulatory steps. What remains less well characterized is to what extent mRNA processing and export regulate gene_expression. The resulting effective transport rates have not been . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or E-mail:

If you don't have an account, you can create one here.