Kinetics of spontaneous and ef-g-accelerated rotation of ribosomal subunits

HIGHLIGHTS

  • who: Heena Sharma from the Max Planck Institute for Biophysical Chemistry, Göttingen, Germany have published the article: Kinetics of Spontaneous and EF-G-Accelerated Rotation of Ribosomal Subunits, in the Journal: (JOURNAL) of August/23,/2016
  • what: The authors show that EF-G binding substantially accelerates CCW rotation, such that it becomes much faster than tRNA-mRNA translocation, whereas CW rotation is concomitant with translocation. The authors determined the rates of spontaneous and EF-G-induced subunit rotation by ensemble kinetics and compared them to those of peptide_bond formation and translocation. The authors show . . .

     

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